Gene targeting ruined my life

While we're blathering about science, the recent award of a Nobel prize to Mario Capecchi, Martin Evans and Oliver Smithies made me remember how much I used to curse their blasted brains during the PhD years. You guys deserve a Nobel prize for making 3 years of my nascent scientific life hell. Then again, without your pioneering work, there'd be no work for the skill-less people in the world like me.